• Association between anthropometry and lifestyle factors and risk of B-cell lymphoma: An exposome-wide analysis 

      Hosnijeh, Fatemeh Saberi; Casabonne, Delphine; Nieters, Alexandra; Solans, Marta; Naudin, Sabine; Ferrari, Pietro; McKay, James D.; Benavente, Yolanda; Weiderpass, Elisabete; Freisling, Heinz; Severi, Gianluca; Ruault, Marie-Christine Boutron; Bonet, Catalina; Besson, Caroline; Agnoli, Claudia; Barricarte, Aurelio; Christakoudi, Sofia; Masala, Giovanna; Knuppel, Anika; Sacerdote, Carlotta; Bueno-De-Mesquita, Bas; Tumino, Rosario; Huerta, José María; Schulze, Matthias B.; Kaaks, Rudolf; Amiano, Pilar; Barranco, Miguel Rodriguez; Canzian, Federico; Späth, Florentin; Jerkeman, Mats; Rylander, Charlotta; Tjønneland, Anne; Olsen, Anja; Borch, Kristin Benjaminsen; Vermeulen, Roel (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-31)
      To better understand the role of individual and lifestyle factors in human disease, an exposome‐wide association study was performed to investigate within a single‐study anthropometry measures and lifestyle factors previously associated with B‐cell lymphoma (BCL). Within the European Prospective Investigation into Cancer and nutrition study, 2402 incident BCL cases were diagnosed from 475 426 ...
    • The association between body fatness and mortality among breast cancer survivors: results from a prospective cohort study 

      Bonet, Catalina; Crous-Bou, Marta; Tsilidis, Konstantinos K.; Gunter, Marc J.; Kaaks, Rudolf; Schulze, Matthias B.; Turzanski Fortner, Rénee; Antoniussen, Christian S.; Dahm, Christina C.; Mellemkjær, Lene; Tjønneland, Anne; Amiano, Pilar; Ardanaz, Eva; Colorado-Yohar, Sandra M.; Rodriguez-Barranco, Miguel; Tin Tin, Sandar; Agnoli, Claudia; Masala, Giovanna; Panico, Salvatore; Sacerdote, Carlotta; May, Anne M.; Borch, Kristin Benjaminsen; Rylander, Karin Charlotta Maria; Skeie, Guri; Christakoudi, Sofia; Aune, Dagfinn; Weiderpass, Elisabete; Dossus, Laure; Riboli, Elio; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-29)
      Evidence linking body fatness to breast cancer (BC) prognosis is limited. While it seems that excess adiposity is associated with poorer BC survival, there is uncertainty over whether weight changes reduce mortality. This study aimed to assess the association between body fatness and weight changes pre- and postdiagnosis and overall mortality and BC-specific mortality among BC survivors. Our study ...
    • Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study 

      Baumeister, Sebastian E.; Schlesinger, Sabrina; Aleksandrova, Krasimira; Jochem, Carmen; Jenab, Mazda; Gunter, Marc J.; Overvad, Kim; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Fournier, Agnès; Kühn, Tilman; Kaaks, Rudolf; Pischon, Tobias; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; La Vecchia, Carlo; Masala, Giovanna; Panico, Salvatore; Fasanelli, Francesca; Tumino, Rosario; Grioni, Sara; Bueno-de-Mesquita, Hendrik Bastiaan; Vermeulen, Roel; May, Anne M.; Borch, Kristin Benjaminsen; Oyeyemi, Sunday Oluwafemi; Ardanaz, Eva; Rodríguez-Barranco, Miguel; Chirlaque López, María Dolores; Felez-Nobrega, Mireia; Sonestedt, Emily; Ohlsson, Bodil; Hemmingsson, Oskar; Werner, Mårten; Perez-Cornago, Aurora; Ferrari, Pietro; Stepien, Magdalena; Freisling, Heinz; Tsilidis, Konstantinos K.; Ward, Heather; Riboli, Elio; Weiderpass, Elisabete; Leitzmann, Michael F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-22)
      <i>Background & Aims</i> - To date, evidence on the association between physical activity and risk of hepatobiliary cancers has been inconclusive. We examined this association in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC).<p><p> <i>Methods</i> - We identified 275 hepatocellular carcinoma (HCC) cases, 93 intrahepatic bile duct cancers (IHBCs), and 164 non-gallbladder ...
    • Association of Mediterranean diet with survival after breast cancer diagnosis in women from nine European countries: results from the EPIC cohort study 

      Castro-Espin, Carlota; Bonet, Catalina; Crous-Bou, Marta; Nadal-Zaragoza, Núria; Tjønneland, Anne; Mellemkjær, Lene; Hajji-Louati, Mariem; Truong, Thérèse; Katzke, Verena; Le Cornet, Charlotte; Schulze, Matthias B.; Jannasch, Franziska; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Di Girolamo, Chiara; Skeie, Guri; Borch, Kristin Benjaminsen; Olsen, Karina Standahl; Sánchez, Maria-Jose; Amiano, Pilar; Chirlaque, María-Dolores; Guevara, Marcela; Sund, Malin; Bodén, Stina; Gunter, Marc J.; Gonzalez-Gil, Esther M.; Weiderpass, Elisabete; Aguilera-Buenosvinos, Inmaculada; Tsilidis, Kostas K.; Heath, Alicia K.; Aune, Dagfinn; Dossus, Laure; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-26)
      Background - The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. We aimed to investigate whether adherence to Mediterranean diet prior to diagnosis is associated with overall and BC-specific mortality.<p> <p>Methods - A total of 13,270 incident breast ...
    • Associations Between Self-Rated Health and Mortality in the Norwegian Women and Cancer (NOWAC) Study 

      Killie, Ida Løken; Braaten, Tonje Bjørndal; Lorem, Geir Fagerjord; Borch, Kristin Benjaminsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-20)
      Purpose: We investigated the association between self-rated health (SRH) and cancer incidence and SRH and all-cause mortality among Norwegian women.<p> <p>Population and Methods: We used data from 110,104 women in the Norwegian Women and Cancer (NOWAC) cohort aged 41– 70 years at baseline. We used flexible parametric survival analysis with restricted cubic splines to calculate hazard ratios (HRs) ...
    • Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study 

      Sedlmeier, Anja M.; Viallon, Vivian; Ferrari, Pietro; Peruchet-Noray, Laia; Fontvieille, Emma; Amadou, Amina; Seyed Khoei, Nazlisadat; Weber, Andrea; Baurecht, Hansjörg; Heath, Alicia K.; Tsilidis, Kostas; Kaaks, Rudolf; Katzke, Verena; Inan-Eroglu, Elif; Schulze, Matthias B.; Overvad, Kim; Bonet, Catalina; Ubago-Guisado, Esther; Chirlaque, María-Dolores; Ardanaz, Eva; Perez-Cornago, Aurora; Pala, Valeria; Tumino, Rosario; Sacerdote, Carlotta; Pasanisi, Fabrizio; Borch, Kristin Benjaminsen; Rylander, Charlotta; Weiderpass, Elisabete; Gunter, Marc J.; Fervers, Béatrice; Leitzmann, Michael F.; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-02)
      Background - Classical anthropometric traits may fail to fully represent the relationship of weight, adiposity, and height with cancer risk. We investigated the associations of body shape phenotypes with the risk of overall and site-specific cancers.<p> <p>Methods - We derived four distinct body shape phenotypes from principal component (PC) analysis on height, weight, body mass index (BMI), waist ...
    • Body Size at Different Ages and Risk of 6 Cancers: A Mendelian Randomization and Prospective Cohort Study 

      Mariosa, Daniela; Smith-Byrne, Karl; Richardson, Tom G.; Ferrari, Pietro; Gunter, Marc J.; Papadimitriou, Nikos; Murphy, Neil; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Riboli, Elio; Muller, David; Purdue, Mark P.; Chanock, Stephen J.; Hung, Rayjean J.; Amos, Christopher I.; O'Mara, Tracy A.; Amiano, Pilar; Pasanisi, Fabrizio; Rodriguez-Barranco, Miguel; Krogh, Vittorio; Tjønneland, Anne; Halkjær, Jytte; Perez-Cornago, Aurora; Chirlaque, María-Dolores; Skeie, Guri; Rylander, Charlotta; Borch, Kristin Benjaminsen; Aune, Dagfinn; Heath, Alicia K.; Ward, Heather A.; Schulze, Matthias; Bonet, Catalina; Weiderpass, Elisabete; Davey Smith, George; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-19)
      It is unclear if body weight in early life affects cancer risk independently of adult body weight. To investigate this question for 6 obesity-related cancers, we performed univariable and multivariable analyses using 1) Mendelian randomization (MR) analysis and 2) longitudinal analyses in prospective cohorts. Both the MR and longitudinal analyses indicated that larger early life body size was ...
    • The burden of colon cancer attributable to modifiable factors—The Norwegian Women and Cancer Study 

      Lukic, Marko; Licaj, Idlir; Laaksonen, Maarit A.; Weiderpass, Elisabete; Borch, Kristin Benjaminsen; Rylander, Charlotta (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)
      Colon cancer is the second most frequently diagnosed cancer in women in Norway, where incidence rates of colon cancer increased 3-fold between 1955 and 2014, for unknown reasons. We aimed to assess the burden of colon cancer attributable to modifiable risk factors in Norwegian women using the data from the Norwegian Women and Cancer (NOWAC) study. Self-reported information from 35 525 women from the ...
    • Combined impact of healthy lifestyle factors on colorectal cancer: A large European cohort study 

      Aleksandrova, Krasimira; Pischon, Tobias; Jenab, Mazda; Bueno-de-Mesquita, Bas H; Fedirko, Veronika; Norat, Teresa; Romaguera, Dora; Knüppel, Sven; Boutron-Ruault, Marie-Christine; Dossus, Laure; Dartois, Laureen; Kaaks, Rudolf; Li, Kuanrong; Tjønneland, Anne; Overvad, Kim; Quirós, José Ramón; Buckland, Genevieve; Sanchez, Maria Jose; Dorronsoro, Miren; Chirlaque, Maria-Dolores; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nicholas J; Bradbury, Kathryn E; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Siersema, Peter D.; Peeters, Petra HM; Ljuslinder, Ingrid; Johansson, Ingegerd; Ericson, Ulrika; Ohlsson, Bodil; Weiderpass, Elisabete; Skeie, Guri; Borch, Kristin Benjaminsen; Rinaldi, Sabina; Romieu, Isabelle; Kong, Joyce; Gunter, Marc J; Ward, Heather A; Riboli, Elio; Boeing, Heiner (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Combined Lifestyle Behaviors and the Incidence of Common Cancer Types in the Norwegian Women and Cancer Study (NOWAC) 

      Chen, Sairah Lai Fa; Braaten, Tonje Bjørndal; Borch, Kristin Benjaminsen; Ferrari, Pietro; Sandanger, Torkjel M; Nøst, Therese Haugdahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-16)
      <i>Introduction</i>: Only a small number of studies have examined the impact of combined lifestyle behaviors on cancer incidence, and never in a Norwegian population.<br><br> <i>Purpose</i>: To examine linear and nonlinear associations of combined lifestyle factors, assessed through a healthy lifestyle index (HLI), with the incidence of postmenopausal breast, colorectal, lung, postmenopausal ...
    • Competing mortality risks analysis of prediagnostic lifestyle and dietary factors in colorectal cancer survival: the Norwegian Women and Cancer Study 

      Oyeyemi, Sunday Oluwafemi; Braaten, Tonje; Skeie, Guri; Borch, Kristin Benjaminsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-30)
      <i>Background</i> - It remains unclear whether or which prediagnostic lifestyle and dietary factors influence colorectal cancer (CRC) survival following diagnosis. This study used competing mortality risks analysis to evaluate the association between these factors and CRC survival.<p> <p><i>Methods</i> - A total of 96 889 cancer-free participants of the Norwegian Women and Cancer Study completed ...
    • Criterion validity of a 10-category scale for ranking physical activity in Norwegian women 

      Borch, Kristin Benjaminsen; Ekelund, Ulf; Brage, Søren; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Accurate measurement of physical activity (PA) is critical to establish dose-response relationships with various health outcomes. We compared the self-administered PA questionnaire from the Norwegian Women and Cancer Study (NOWAC) with a criterion method in middle-aged Norwegian women. A sample of 177 randomly recruited healthy women attended two clinical visits approximately 4-6 months apart. At ...
    • Cross-sectional associations of objectively measured physical activity, cardiorespiratory fitness and anthropometry in european adults 

      Wientzek, A; Tormo Diaz, MJ; Castano, JMH; Amiano, P; Arriola, L; Overvad, K; Østergaard, JN; Charles, MA; Fagherazzi, G; Palli, D; Bendinelli, B; Skeie, Guri; Borch, Kristin Benjaminsen; Wendel-Vos, W; De Hollander, E; May, AM; Den Ouden, ME; Trichopoulou, A; Valanou, E; Soderberg, S; Franks, PW; Brage, S; Vigl, M; Boeing, H; Ekelund, Ulf (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-06-26)
      Objective: To quantify the independent associations between objectively measured physical activity (PA), cardiorespiratory fitness (CRF), and anthropometry in European men and women.<p> <p>Methods: 2,056 volunteers from 12 centers across Europe were fitted with a heart rate and movement sensor at 2 visits 4 months apart for a total of 8 days. CRF (ml/kg/min) was estimated from an 8 minute ramped ...
    • Exploring geographical differences in the incidence of colorectal cancer in the Norwegian women and cancer study: A population-based prospective study 

      Oyeyemi, Sunday Oluwafemi; Braaten, Tonje; Botteri, Edoardo; Berstad, Paula; Borch, Kristin Benjaminsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-08)
      <i>Purpose</i>: Norway has experienced an unexplained, steep increase in colorectal cancer (CRC) incidence in the last half-century, with large differences across its counties. We aimed to determine whether geographical distribution of lifestyle-related CRC risk factors can explain these geographical differences in CRC incidence in Norwegian women.<p><p> <i>Methods</i>: We followed a nationally ...
    • Healthy lifestyle and the risk of pancreatic cancer in the EPIC study 

      Naudin, Sabine; Viallon, Vivian; Hashim, Dana; Freisling, Heinz; Jenab, Mazda; Weiderpass, Elisabete; Perrier, Flavie; McKenzie, Fiona; Bueno-de-Mesquita, Hendrik Bastiaan; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Mancini, Francesca R.; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kaaks, Rudolf; Bergmann, Manuela; Boeing, Heiner; Peppa, Eleni; Karakatsani, Anna; Trichopoulou, Antonia; Pala, Valeria; Masala, Giovana; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; May, Anne M.; van Gils, Carla H.; Rylander, Charlotta; Borch, Kristin Benjaminsen; Chirlaque López, María Dolores; Sánchez, Mariá-José; Ardanaz, Eva; Quirós, José Ramón; Amiano Exezarreta, Pilar; Sund, Malin; Drake, Isabel; Regnér, Sara; Travis, Ruth C.; Wareham, Nick; Aune, Dagfinn; Riboli, Elio; Gunter, Marc J.; Duell, Eric J.; Brennan, Paul; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-28)
      Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association between the Healthy Lifestyle Index (HLI) and PC risk was examined. Within the European Prospective Investigation into Cancer and Nutrition cohort, 1113 incident PC (57% women) ...
    • Heterogeneity of colorectal cancer risk factors by anatomical subsite in 10 European countries: A multinational cohort study 

      Murphy, Neil; Ward, Heather A.; Jenab, Mazda; Rothwell, Joseph A.; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Kvaskoff, Marina; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Aleksandrova, Krasimira; Weiderpass, Elisabete; Skeie, Guri; Borch, Kristin Benjaminsen; Tjønneland, Anne; Kyrø, Cecilie; Overvad, Kim; Dahm, Christina C.; Jakszyn, Paula; Sánchez, María-José; Gil, Leire; Huerta, José María; Barricarte, Aurelio; Quirós, José Ramón; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Trichopoulou, Antonia; La Vecchia, Carlo; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Fasanelli, Francesca; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Peeters, Petra H.M.; Gylling, Björn; Myte, Robin; Jirström, Karin; Berntsson, Jonna; Xue, Xiaonan; Riboli, Elio; Cross, Amanda J.; Gunter, Mark J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-26)
      <i>Background & Aims</i> - Colorectal cancer located at different anatomical subsites may have distinct etiologies and risk factors. Previous studies that have examined this hypothesis have yielded inconsistent results, possibly because most studies have been of insufficient size to identify heterogeneous associations with precision.<p><p> <i>Methods</i> - In the European Prospective Investigation ...
    • Life-Course Trajectories of Physical Activity and Melanoma Risk in a Large Cohort of Norwegian Women 

      Perrier, Flavie; Ghiasvand, Reza; Lergenmuller, Simon; Robsahm, Trude Eid; Green, Adele C.; Borch, Kristin Benjaminsen; Sandanger, Torkjel M; Weiderpass, Elisabete; Rueegg, Corina Silvia; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-22)
      Purpose: Physical activity (PA) is a cornerstone in disease prevention and varies throughout life. A pooled analysis of cohort studies and a meta-analysis of cohort studies found positive associations between PA and melanoma risk. However, previous studies focused on PA at specific ages and often lacked information on ultraviolet radiation (UVR) exposure. Using the population-based Norwegian Women ...
    • Mediating Role of Lifestyle Behaviors in the Association between Education and Cancer: Results from the European Prospective Investigation into Cancer and Nutrition 

      Macciotta, Alessandra; Catalano, Alberto; Giraudo, Maria Teresa; Weiderpass, Elisabete; Ferrari, Pietro; Freisling, Heinz; Colorado-Yohar, Sandra M.; Santiuste, Carmen; Amiano, Pilar; Heath, Alicia K.; Ward, Heather A.; Christakoudi, Sofia; Vineis, Paolo; Singh, Deependra; Vaccarella, Salvatore; Schulze, Matthias B.; Hiensch, Anouk E.; Monninkhof, Evelyn M.; Katzke, Verena; Kaaks, Rudolf; Tumino, Rosario; Lazzarato, Fulvio; Milani, Lorenzo; Agudo, Antonio; Dahm, Christina C.; Baglietto, Laura; Perduca, Vittorio; Severi, Gianluca; Grioni, Sara; Panico, Salvatore; Ardanaz, Eva; Borch, Kristin Benjaminsen; Benebo, Faith Owunari; Braaten, Tonje; Sánchez, Maria-Jose; Giachino, Claudia; Sacerdote, Carlotta; Ricceri, Fulvio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-09)
      Background: Many studies have shown that socioeconomic position (SEP) is associated with the incidence of malignant tumors at different sites. This study aims to estimate the association between educational level (as proxy for SEP) and cancer incidence and to understand whether the observed associations might be partially explained by lifestyle behaviors.<p> <p>Methods: The analyses were performed ...
    • Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition 

      Kliemann, Nathalie; Viallon, Vivian; Murphy, Neil; Beeken, Rebecca J.; Rothwell, Joseph A.; Rinaldi, Sabina; Assi, Nada; van Roekel, Eline H.; Schmidt, Julie A.; Borch, Kristin Benjaminsen; Agnoli, Claudia; Rosendahl, Ann H.; Sartor, Hanna; Huerta, José María; Tjønneland, Anne; Halkjær, Jytte; Bueno-de-Mesquita, Bas; Gicquiau, Audrey; Achaintre, David; Aleksandrova, Krasimira; Schulze, Matthias B.; Heath, Alicia K.; Tsilidis, Konstantinos K.; Masala, Giovanna; Panico, Salvatore; Kaaks, Rudolf; Fortner, Renée T.; Van Guelpen, Bethany; Dossus, Laure; Scalbert, Augustin; Keun, Hector C.; Travis, Ruth C.; Jenab, Mazda; Johansson, Mattias; Ferrari, Pietro; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-30)
      Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study.<p> <p>Methods: Targeted mass spectrometry ...
    • No association between physical activity and primary melanoma thickness in a cohort of Norwegian women 

      Perrier, Flavie; Robsahm, Trude Eid; Ghiasvand, Reza; Borch, Kristin Benjaminsen; Braaten, Tonje; Weiderpass, Elisabete; Rüegg, Corina Silvia; Greene, Adele C; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-21)
      Knowledge about factors associated with melanoma thickness, the most important prognostic factor for localized primary melanoma survival,1 may help reduce the risk of melanoma deaths. Previously reported associations of melanoma thickness with pigmentary characteristics, number of naevi, diet quality and body mass index (BMI)2–4 may be explained by behavioural and biological mechanisms. Physical ...